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يستعمل دواء أكلاستا 5 مجم / 100 ملaclasta 5mg/100ml soln. for inf. osteoporosis.bisphosphonates osteoporosis.bisphosphonates
about zoledronic acid -third-generation bisphosphonate osteoclastic bone resorption inhibitor(calcium regulator). -mechanism of action of zoledronic acid -zoledronate is a third generation bisphosphonate. it is an analogue of pyrophosphate in which the p-o-p bond is replaced by a non hydrolysable p-c-p bond. with divalent cation such as ca2+ (calcium ion) in the bone they can capable to form chelating complex and form a three dimensional structure. it has high affinity for active remodeling site in the bone. bisphosphonate retard formation and dissolution of hydroxy apatite crystals within bone and other site. bisphosphonate remain in the matrix until the bone is remolded and then released in the acid environment of the resorption lacunae beneath the osteoclasts as the overlying mineral matrix is dissolved. it produces antiresorptive action by osteoclasts apoptosis activity and by inhibition of components of the cholesterol biosynthetic pathway.
تركيبة دواءأكلاستا 5 مجم / 100 ملaclasta 5mg/100ml soln. for inf.
يتركب هذا الدواء من :zoledronic acid
الشركة المنتجة لدواءأكلاستا 5 مجم / 100 ملaclasta 5mg/100ml soln. for inf.
هذا الدواء من انتاج شركة novartis
جرعة دواءأكلاستا 5 مجم / 100 مل
Welcome to Dlildwa, specifically the page of aclasta 5mg/100ml soln. for inf..
تم استعراض بدائل هذا الدواء 631 مرة