يستعمل دواء بروفينال 400مجم 24 اقراصprofinal 400mg 24 tab. nsaid.propionic acid derivatives nsaid.propionic acid derivatives

about ibuprofen -nsaid a propionic acid derivative analgesic and anti-inflammatory. - -mechanism of action of ibuprofen -ibuprofen has analgesic anti-inflammatory and antipyretic action. it acts by inhibiting prostaglandin (pgs) synthesis and their release at the site of injury. prostaglandins cause tenderness and amplify the action of other algesics. ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. it also inhibits platelet aggregation and prolongs bleeding time. - -indications for ibuprofen -1.rheumatoid arthritis -2.ankylosing spondylitis -3.acute gout -4.joint disorders e.g. inflammatory disease in joints crystal deposition in the joints -5.osteoarthritis -6.for the relief of fever pain and inflammation in dental minor surgery and orthopedic -7.dysmenorrhoea -8.juvenile arthritis -9.migraine -10.patent ductus arteriosus(iv)