يستعمل دواء سارتاليس 300مجم 14 اقراصsartaless 300mg 14 scored tab. anti-hypertensive.angiotensin blocker anti-hypertensive.angiotensin blocker

about irbesartan -angiotensin ii receptor blocker a non-peptide compound antihypertensive. - -mechanism of action of irbesartan -it is a competitive antagonist of angiotensin-2 at at-1 receptor. it decreases peripheral resistance and lowers bp in hypertensive individuals. it blocks all overt actions of angiotensin-2 such as: - 1. vasoconstriction 2. central & peripheral sympathetic stimulus 3. release of aldosterone and adrenaline 4. salt and water reabsorption 5. central actions like thirst vasopressin release and growth promoting actions on heart and blood vessels. - -indications for irbesartan -1. hypertension - -interactions for irbesartan -no significant interactions have been found in concomitant use with hydrochlorothiazide digoxin warfarin and nifedipine.