يستعمل دواء سيجماجريل 75مجم 20 اقراصsigmagrel 75mg 20 f.c. tab. antiplatlet.adp receptor blocker antiplatlet.adp receptor blocker

about clopidogrel -thienopyridine class platelet aggregation inhibitor antithrombic anti platelet agent. -mechanism of action of clopidogrel -the drug exerts it`s antithrombotic action by interfering with platelet aggregation. it alters surface receptors in platelets and inhibits adp induced platelet-fibrinogen and platelet-platelet binding and prevents platelet aggregation. it blocks g-protein coupled p2yac type of inhibitory purinergic receptors which mediates adenylyl cyclase inhibition by adp. it prolongs bleeding time. - -indications for clopidogrel -1. to reduce atherosclerotic events -2. thrombotic disorders -3. prevention of stroke -4. prophylaxis of myocardial infarction -5. peripheral vascular diseases -6. coronary artery diseases.