يستعمل دواء سيجماتاكسيم 500مج امبولsigmataxim 500 mg i.v. / i.m. vial antibiotic.cephalosporin.third-generation antibiotic.cephalosporin.third-generation

about cefotaxime -third generation cephalosporin parenteral antibiotic. - -mechanism of action of cefotaxime -cefotaxime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. cefotaxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like cefotaxime - -indications for cefotaxime -1.meningitis -2.resistant hospital acquired infections -3.septicemia -4.infections in immunocompromised patients -5.urinary tract &genital tract infections -6.surgical prophylaxis -7.skin & soft tissue infections -8.bone & joint infections -9.gonorrhea. - -interactions for cefotaxime -synergy with aminoglycosides.