يستعمل دواء سبازموريست 20مجم 20 اقراصspasmorest 20 mg 20 tabs. anti-muscarinic.irritable bowel syndrome anti-muscarinic.irritable bowel syndrome

about dicyclomine -anticholinergic antimuscarinic antispasmodic and in urinary incontinence. - -mechanism of action of dicyclomine -dicyclomine is an anticholinergic drug. it exerts its action by inhibiting muscarinic (((cholinergic))) receptors on smooth muscles and prevents the effect of acetylcholine. inhibition of acetylcholine produces relaxation of smooth muscles of gastrointestinal tract and genitourinary tract and reduces the painful spasm and cramp. it inhibits gastrointestinal propulsive motility and reduces gastric acid secretion. it also has a direct relaxant effect on smooth muscle. it readily crosses the blood brain barrier and produces cns effects. - -indications for dicyclomine -1. irritable bowel syndrome -2.colicky pain - -typical dosage for dicyclomine -adult: -oral: 80 mg / day in 4 divided doses 30 - 60 minutes before meals. depending on the patient`s response dose can be increased to 160 mg / day in 4 divided doses after 1 week. -