يستعمل دواء توبرانو 4مجم 20 اقراصtoprano 4mg 20 f.c.tab. nsaid.oxicam nsaid.oxicam

about lornoxicam -non-steroidal anti-inflammatory drug (nsaid) of the oxicam class with analgesic (pain relieving) anti-inflammatory and antipyretic (fever reducing) properties. it is available in oral and parenteral formulations. - -mechanism of action of lornoxicam -like other nsaids lornoxicam inhibits prostaglandin biosynthesis by blocking the enzyme cyclooxygenase. lornoxicam inhibits both isoforms in the same concentration range that is the ratio of cox-1 inhibition to cox-2 inhibition is 1:1. it readily penetrates into the synovial fluid. - -interactions for lornoxicam -1.vitamin k antagonists like warfarin increases the risk of bleeding. -2.ciclosporin can lead to reduced kidney function and to acute renal failure in rare cases. -3.lornoxicam can also increase the adverse effects of lithium methotrexate and digoxin and its derivatives. -4.the effect of diuretics ace inhibitors and angiotensin ii receptor antagonists can be reduced but this is only relevant in patient