يستعمل دواء تريتوفلامين 0.025% كريم 20جمtretoflamin 0.025% cream 20 gm glucocorticoid glucocorticoid

about fluocinolone acetonide -a synthetic hydrocortisone derivative vasoprotective reduce skin inflammation. -mechanism of action of fluocinolone acetonide -fluocinolone is a topical high potency glucocorticoid. -the drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. this structural change allows it`s migration in to the nucleus and then binding to specific sites on the dna which leads to transcription of specific m-rna and which ultimately regulates protein synthesis. it exerts highly selective glucocorticoid action. it stimulates the enzymes needed to decrease the inflammatory response.