يستعمل دواء تريكسام 500مجم 20 اقراصtrexam 500mg 20 tab. bleedding.fibrinolytics inhibitors bleedding.fibrinolytics inhibitors

about tranexamic acid -lysine analog hemostatic competitive plasminogen activationinhibitor antifibrinolytic antihemophilic. -mechanism of action of tranexamic acid -tranexamic acid exerts antifibrinolytic effect by forming a reversible complex with plasminogen through the lysine binding site of fibrin and thus displaces the plasminogen from the fibrin surface ; preventing the binding of plasmin to fibrinogen or fibrin monomers. it inhibits the activation of plasminogen (i.e. formation of plasmin). it also acts as a weak non competitive inhibitor of plasmin and blocks it`s action on fibrin. -indications for tranexamic acid -1.surgical procedures -2.menorrhagia -3. metrorrhagia -4.post partum haemorrhage -5.haemorrhage after abortion -6.haemorrhage due to contraceptive device insertion -7.tooth extractions and haemorrhage in other dental procedures -8.epistaxis -9.haemoptysis -10.gastrointestinal bleeding -11.prostatectomy -12.tonsillectomy -13.fibrinolysis -