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يستعمل دواء تريكوجل 500مجم 12 اقراصtrichogyl 500mg 12 f.c.tab. antiprotozoal.nitroimidazole antiprotozoal.nitroimidazole
about metronidazole -a nitroimidazole antibiotic anti-infective antiprotozoal amebicide. -mechanism of action of metronidazole -metronidazole is nitro imidazoles which have broad spectrum cidal activity against protozoa and some anaerobic bacteria. its selective toxicity to anaerobic microbes involves 1. drug enters the cell by diffusion 2. nitro group of drug is reduced by redox proteins present only in anaerobic organisms to reactive nitro radical which exerts cytotoxic action by damaging dna and other critical biomolecules. 3. dna helix destabilization & strand breakage has been observed. -indications for metronidazole -1.amoebiasis -2.giardiasis -3.trichomonas vaginitis -4.pseudo membranous enterocolitis -5.anaerobic bacterial infections after surgery brain abscess & endocarditis -6.helicobacter pylori infections -7.ulcerative gingivitis
تركيبة دواءتريكوجل 500مجم 12 اقراصtrichogyl 500mg 12 f.c.tab.
يتركب هذا الدواء من :metronidazole
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جرعة دواءتريكوجل 500مجم 12 اقراص
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