يستعمل دواء فانكومكس 1جم فيال vancomix 1g i.v. vial tricyclic glycopeptide antibiotic tricyclic glycopeptide antibiotic

about vancomycin -a tricyclic glycopeptide antibiotic. -mechanism of action of vancomycin -vancomycin binds to the terminal dipeptide sequence of peptidoglycan and inhibits the association and cross linking of peptidoglycan and as the result inhibit cell wall synthesis -indications for vancomycin -1. endocarditis -2. pseudomembranous enterocolitis -3. methicillin resistant staphylococcus aureus infection -4. staphylococcal enterocolitis -interactions for vancomycin -anion-exchange resins: antagonism of oral vancomycin by cholestyramine. -aminoglycosides: risk of nephrotoxicity may be increased. -anaesthetics: erythema and histamine like flushing in children. -nondepolorizing muscle relaxants: the neuromuscular blockade may be enhanced.