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about zolmitriptan -selective serotonin (5ht1) agonists anti migraine -mechanism of action of zolmitriptan -zolmitriptan is a selective agonist for serotonin (5ht1 receptors). it relieves migraine by selective constriction of intracranial blood vessels neuropeptide release inhibition and decreased transmission in the trigeminal pain pathway -indications for zolmitriptan -acute migraine attack -interactions for zolmitriptan -increased risk of serotonin syndrome with ssri selective serotonin- and norepinephrine-reuptake inhibitors (snri) -increased zolmitriptan concentrations with cimetidine quinolone antibacterials and drugs that inhibit the cytochrome p450 isoenzyme cyp1a2
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