يستعمل دواء بوسبار 10 مجم 20 قرصbuspar 10mg 20 tab. psychiatric.anxiolytics-hypnotics psychiatric.anxiolytics-hypnotics

about buspirone -psychotropic drug serotonin 5-ht1a receptor partial agonist weak dopamine (d2) antagonist azaspirodecanediones derivative sedative anxiolytic agent. - -mechanism of action of buspirone -buspirone has a partial agonistic action on 5ht1a receptor and it stimulates presynaptic autoreceptors. this will produce a decrease in serotonin neuronal activity. it also has antagonistic action on post synaptic 5ht1a receptor. buspirone has a weak dopamine (d2) antagonistic action. mood elevation may be due to facilitation of noradrenergic system. - -indications for buspirone -anxiety - -typical dosage for buspirone -adult: 15 - 30 mg / day in 3 divided dose -initial dose: 15 mg / day in 3 divided dose. dose can be gradually increased in every 3 days. maximum daily dose: 60 mg / day