يستعمل دواء سيبالافيل 20مجم 4 اقراصcipalafil 20 mg 4 tabs. s. tonic s. tonic

about tadalafil -a phosphodiesterase 5 enzyme inhibitor treating er dysfunction (ed). -mechanism of action of tadalafil -tadalafil is a phosphodiesterase enzyme (pde5) inhibitor. this enzyme is responsible for the degradation cyclic guanosine monophosphate (cgmp) produced in reaction to s. stimulation. the more cgmp is available the more durable the er. tadalafil inhibits the pde5 enzyme preserving cgmp levels therefore aiding er. viability and durability -er. of the p is caused by the filling of the p with blood. filling occurs because the blood vessels that bring blood to the p increase in size and deliver more blood to the p. and at the same time the blood vessels that take blood away from the p. decrease in size and remove less blood from the p. -s. stimulation that leads to an er. causes the production and release of nitric oxide in the p. the nitric oxide causes an enzyme guanylate cyclase