يستعمل دواء كرونوميزون 0.1٪ مرهم 15 جمcronomesone 0.1% oint. 15 gm glucocorticoid glucocorticoid

about betamethasonespotent glucocorticoid anti-inflammatory immunosuppressent.ssmechanism of action of betamethasonesthe drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. this structural change allows it`s migration in to the nucleus and then binding to specific sites on the dna which leads to transcription of specific m-rna and which ultimately regulates protein synthesis. it exerts highly selective glucocorticoid action. it stimulates the enzymes needed to decrease the inflammatory response. ssindications for betamethasones1.inflammatory conditions s2.allergic reactions s3.shock s4.anaphylaxis s5.intra-articular and soft tissue inflammation s6.asthma s7.rheumatoid arthritis s8.adrenal insufficiency s9.tuberculous meningitis s10.respiratory diseases s11.malignancies s12.cerebral oedema s13.collagen diseases s14.addison`s disease s15.simmond`s disease s