يستعمل دواء ايبريوبسين ميلان 100مجم/50مل مل فيالepirubicin mylan 100mg/50ml vial i.v. inf. antineoplastic antineoplastic

about epirubicin -anthracycline anibiotic antineoplastic. -mechanism of action of epirubicin -this anthracycline drug intercalates dna strands which results complex formation it will inhibit dna & rna synthesis. it triggers dna cleavage by inhibiting topoisomerase 2 that leads to cell death. binding of this drug to the cell membrane and plasma proteins involved this compounds cytotoxic effects. epirubicin also generates free radicals that cause cell and dna damage.ssindications for epirubicins1. breast cancer s2. gastric cancer s3. lung cancer s4. lymphomas s5. non hodgkins disease s6. ovarian cancer s7. bladder cancer s8. pediatric soft tissue sarcoma s9. soft tissue sarcoma