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يستعمل دواء جولينوساب 0.5 مجم 4 اقراصgolinosab 0.5mg 4 tab. dopamine agonist and prolactin inhibitor dopamine agonist and prolactin inhibitor
description -cabergoline an ergot derivative is a long-acting dopamine agonist and prolactin inhibitor. it is used to treat hyperprolactinemic disorders and parkinsonian syndrome. cabergoline possesses potent agonist activity on dopamine d2 receptors. - -indication -for the treatment of hyperprolactinemic disorders either idiopathic or due to prolactinoma (prolactin-secreting adenomas). may also be used to manage symptoms of parkinsonian syndrome as monotherapy during initial symptomatic management or as an adjunct to levodopa therapy during advanced stages of disease. - -mechanism of action the dopamine d2 receptor is a 7-transmembrane g-protein coupled receptor associated with gi proteins. in lactotrophs stimulation of dopamine d2 causes inhibition of adenylyl cyclase which decreases intracellular camp concentrations and blocks ip3-dependent release of ca2+ from intracellular stores. decreases in intracellular calcium levels may also be brought about via inhibition of calcium
تركيبة دواءجولينوساب 0.5 مجم 4 اقراصgolinosab 0.5mg 4 tab.
يتركب هذا الدواء من :cabergoline
الشركة المنتجة لدواءجولينوساب 0.5 مجم 4 اقراصgolinosab 0.5mg 4 tab.
هذا الدواء من انتاج شركة sabaa > nexus international pharmaceuticals
جرعة دواءجولينوساب 0.5 مجم 4 اقراص
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