يستعمل دواء هيلسك 40 مجم 14 كبسولةhealsec 40mg 14 caps. peptic ulcer.proton pump inhibitor peptic ulcer.proton pump inhibitor

about omeprazolesproton pump inhibitor substituted benzimidazole anti-secretory antiulcer.smechanism of action of omeprazolesomeprazole is a proton pump inhibitor and it is a prodrug. after administration it diffuses in to the parietal cell of the stomach and accumulates in the secretory canaliculi. in the acidic medium omeprazole is converted to sulfenamide. this sulfenamide covalently interacts with sulfhydryl (sh) group in the proton pump s(h+ k+atpase) and inhibits the exchange of extracellular k+ for intracellular h+ ion. omeprazole irreversibly inhibits proton pumps activity and decreases gastric acid secretion.