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يستعمل دواء كادوميت 250 مجم 30 قرصkadomet 250mg 30 tab antihypertensives.centeral alpha 2 agonist antihypertensives.centeral alpha 2 agonist
about methyldopa -centrally acting alpha-2 agonist a phenylalanine derivative antihypertensive (pregnancy-induced hypertension). -mechanism of action of methyldopa -methyl dopa gets metabolized in the adrenergic neurons to alpha methyl nor adrenaline which acts centrally by stimulating alpha 2 adrenergic receptors in the vasomotor centre to decrease efferent sympathetic activity and total peripheral resistance. it also inhibits renin release from the kidneys and has some direct action on blood vessels. since methyl dopa serves as an alternate substrate to l-aromatic amino acid decarboxylase it ultimately decrease the concentration of dopamine nor-adrenaline epinephrine and serotonin in the cns and periphery.
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يتركب هذا الدواء من :methyldopa
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جرعة دواءكادوميت 250 مجم 30 قرص
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