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يستعمل دواء كيتولاك 30 مجم / 2 مل 5 امبولketolac 30mg/2ml 5 amp. for i.m./i.v. inf. nsaid.acetic acid derivatives nsaid.acetic acid derivatives
mechanism of action ketorolac is a nonsteroidal anti-inflammatory drug (nsaid) chemically related to indomethacin and tolmetin. ketorolac tromethamine is a racemic mixture of [-]s- and [+]r-enantiomeric forms with the s-form having analgesic activity. its antiinflammatory effects are believed to be due to inhibition of both cylooxygenase-1 (cox-1) and cylooxygenase-2 (cox-2) which leads to the inhibition of prostaglandin synthesis leading to decreased formation of precursors of prostaglandins and thromboxanes from arachidonic acid. the resultant reduction in prostaglandin synthesis and activity may be at least partially responsible for many of the adverse as well as the therapeutic effects of these medications. analgesia is probably produced via a peripheral action in which blockade of pain impulse generation results from decreased prostaglandin activity.
تركيبة دواءكيتولاك 30 مجم / 2 مل 5 امبولketolac 30mg/2ml 5 amp. for i.m./i.v. inf.
يتركب هذا الدواء من :ketorolac tromethamine
الشركة المنتجة لدواءكيتولاك 30 مجم / 2 مل 5 امبولketolac 30mg/2ml 5 amp. for i.m./i.v. inf.
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جرعة دواءكيتولاك 30 مجم / 2 مل 5 امبول
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