يستعمل دواء امريفلوكان 150 مجم 2 كبسولةamriflucan 150 mg 2 caps. antifungals.triazoles antifungals.triazoles

about fluconazolesa triazole derivative a board range antifungal.ssmechanism of action of fluconazolesfluconazole is fungicidal or fungistatic depending on the drug concentrations. i t inhibits the conversion of lanosterol to 14 demethyl lanosterol by inhibiting the cytochromep450 enzyme 14 alpha demethylase and impair ergosterol synthesisssinteractions for fluconazolescimetidine: decreased efficacy of fluconazole. scyclosporine: increase in serum cyclosporine plasma concentration. shydrochlorothiazide: reduction in renal clearance of fluconazole. sphenytoin: efficacy of phenytoin enhanced. srifampicin: efficacy of fluconazole decreased higher dosage required. ssulfonylureas: efficacy of tolbutamide glyburide and glipizide increased. swarfarin: potentiates the anticoagulant effect resulting in increase in prothrombin time. ssindications for fluconazoles1.oesophageal candidiasis s2.oropharyngeal candidiasis s3.vaginal candidiasis s4.systemic candidiasis s5.cryptoc