يستعمل دواء larithrocin 250mg 14 f.c.tab. antibiotic.macrolide antibiotic.macrolide

about clarithromycin -it is a new macrolide antimicrobial drug.it is the most effective macrolide against haemophilus influenzae chlamydia trachomaitis and chlamydia pneumoniae. - -mechanism of action of clarithromycin -clarithromycin is a member of macrolide antibiotic.it binds to the 50s sub unit of bacterial ribosome and inhibits translocation.ie:they interfere with the transfer of the newly formed peptide chain from the a site to the p site and fails to expose the a site .so that a site is unable to bind with the next aminoacyl trna complex. this leads to premature termination of amino acid chain and there by inhibits protein synthesis. - -indications for clarithromycin -1.tonsilitis -2.pharyngitis -3.pneumonia -4.skin and soft tissue infections -5.bronchitis -6.otitis media -7.prophylaxis of mac -8.leprosy -9.acne -10.nocardiosis