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يستعمل دواء نيرين 50مجم/5مل 5 محلول امبولnyrin 50mg/5ml 5 sol. in amp. for i.v inj. folic acid derivative folic acid derivative
indication -for the treatment of osteosarcoma (after high dose methotrexate therapy). used to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists and to treat megaloblastic anemias due to folic acid deficiency. also used in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer. - -mechanism of action -as leucovorin is a derivative of folic acid it can be used to increase levels of folic acid under conditions favoring folic acid inhibition (following treatment of folic acid antagonists such as methotrexate). leucovorin enhances the activity of fluorouracil by stabilizing the bond of the active metabolite (5-fdump) to the enzyme thymidylate synthetase.
تركيبة دواءنيرين 50مجم/5مل 5 محلول امبولnyrin 50mg/5ml 5 sol. in amp. for i.v inj.
يتركب هذا الدواء من :leucovorin calcium=folinic acid=calcium folinate
الشركة المنتجة لدواءنيرين 50مجم/5مل 5 محلول امبولnyrin 50mg/5ml 5 sol. in amp. for i.v inj.
هذا الدواء من انتاج شركة hikma specialized pharmaceuticals
جرعة دواءنيرين 50مجم/5مل 5 محلول امبول
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تم استعراض بدائل هذا الدواء 246 مرة
nyrin 50mg/5ml 5 sol. in amp. for i.v inj.
اذهب الى الدواءbendafolin 50mg soln. for i.m./i.v. inj. or inf.
اذهب الى الدواءfolinobiogen 300mg/30ml vial(n/a yet)
اذهب الى الدواءbendafolin 10mg/ml soln. for i.m./i.v. inj. or inf.
اذهب الى الدواءfolinobiogen 50mg/5ml vial(n/a yet)
اذهب الى الدواء