يستعمل دواء اوستيوسيجما 2جم 14 اكياسosteosigma 2gm 14 sach. osteoporosis.antiresorptives osteoporosis.antiresorptives

about strontium ranel -bone metabolism modulator antiosteoporotic agent -mechanism of action of strontium ranel -strontium ranelate is an antiosteoporotic agent which both increases bone formation and reduces bone resorption. strontium ranelate stimulates the calcium sensing receptors and leads to the differentiation of pre-osteoblast to osteoblast which increases the bone formation. strontium ranelate also stimulates osteoblasts to secrete osteoprotegerin in inhibiting osteoclasts formed from pre-osteoclasts in relation to the rankl system which leads to the decrease of bone resorption -indications for strontium ranel -postmenopausal osteoporosis -interactions for strontium ranel -food milk and derivative products and medicinal products containing calcium may reduce the bioavailability of strontium ranelate -may reduce the absorption of oral tetracycline and quinolone antibiotics