يستعمل دواء بينكارد 20/10مجم 10 اقراصpencard 20/10mg 10 f.c. tabs. antihyperlipidemic.cholesterol absorption inhibitors.combined with statin antihyperlipidemic.cholesterol absorption inhibitors.combined with statin

indications for atorvastatin + ezetimibe -1.homozygous familial hypercholesterolemia -2.combined hyperlipidaemia -typical dosage for atorvastatin + ezetimibe -adult: 1 tablet / day -about ezetimibe -cholesterol absorption inhibitor 2-azetidinone derivative hypolipidemic agent. -mechanism of action of ezetimibe -it reduces the absorption of cholesterol from the intestine by localising at the brush border of the small intestine where it inhibits the absorption of cholesterol from the diet. specifically it appears to bind to the niemann-pick c1-like 1 (npc1l1) protein on the gastrointestinal tract epithelium a critical mediator of cholesterol absorption. this decreased cholesterol absorption leads to an increase in ldl-cholesterol uptake into cells thus decreasing levels in the blood plasma. -about atorvastatin -hmg-coa reductase inhibitor statins antilipemic agent.