يستعمل دواء اتاراكس 25 مجم 25 قرصatarax 25mg 25 tab. anti-histamine.sedative.first generation anti-histamine.sedative.first generation

about hydroxyzine -a first-generation h1 antagonist piperazine derivative antihistamine antiemetic anxiolytic sedative-hypnotic. -mechanism of action of hydroxyzine -hydroxyzine compete with histamine for h1receptor.it blocks the histamine action s on the effector`s cell surface. it has sedative antiemetic antimuscarinic and spasmolytic property. -antianxiety action: hydroxyzine produces its anxiolytic action through suppression of activity at subcortical levels. -interactions for hydroxyzine -cns depressants (barbiturates hypnotics opiod analgesics): potentiation of cns depressant effect. -maois tcas atropine: potentiate antimuscarinic effects. -aminoglycosides: ototoxicity of aminoglycosides masked. -aminophyllline benzyl penicillin chloramphenicol: incompatible with these drugs. -incompatibility reported with aminophylline benzyl penicillin salts chloramphenicol sodium succinate thioridazine and some soluble barbiturates.