يستعمل دواء بروموكريبتين 2.5 مجم 30 قرصbromocriptine 2.5 mg 30 tab. dopamine agonist dopamine agonist

about bromocriptine -dopamine agonist ergot- alkaloid anti parkinsonsm hypoprolactinemic. - -mechanism of action of bromocriptine -bromocriptine is a dopaminergic agonist. it acts as a potent agonist on d2 receptor and partial agonist or antagonist on d1 receptor. bromocriptine produces a decrease in dopamine turnover with increase in dopamine content of the brain and decreases the metabolism of dopamine. the increase in dopamine concentration produces effect in parkinson`s disease. -since dopamine is a neurotransmitter in the brain it can produces various motor behavioural and endocrine effects. -hormonal action: bromocriptine inhibits synthesis and release of prolactin from pituitary lactotrope cell by acting as a d2 agonist. - -indications for bromocriptine -1.parkinson`s disease -2.amenorrhea and galactorrhea associated with hyperprolactinemia -3.acromegaly -4.hepatic encephalopathy -5.premenstrual syndrome -6.cushing`s syndrome -7.suppression of established lactation.