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يستعمل دواء كولوسالازين اي سي 500 مجم 20 قرصcolosalazine-ec 500mg 20 enteric coated tab. ulcerative colitis ulcerative colitis
about sulphasalazine -composed of 5-aminosalicylic acid and sulfapyridine anti-infective (in inflammatory bowel disease) anti arthritic. -mechanism of action of sulphasalazine -sulfasalazine exerts its anti-inflammatory action by inhibiting lipoxygenase enzyme. this will leads to decreased production of pro-inflammatory leukotrienes (ltb4) and 5-hydroxy eicosa tetra enoic acids (hete) in the intestinal wall. it inhibits the production of inflammatory mediators like interleukin-1 tumor necrosis factor-alpha etc -indications for sulphasalazine -1. ulcerative colitis -2. crohn`s disease -3. rheumatoid arthritis -4. diarrhea -interactions for sulphasalazine -folic acid : signs of folic deficiency with sulphasalazine. -digoxin : possibly reduced efficacy of digoxin.
تركيبة دواءكولوسالازين اي سي 500 مجم 20 قرصcolosalazine-ec 500mg 20 enteric coated tab.
يتركب هذا الدواء من :sulphasalazine
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جرعة دواءكولوسالازين اي سي 500 مجم 20 قرص
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