يستعمل دواء ديكساميثازون سيجما 8 مجم / 2 مل 5 امبولdexamethasone-sigma 8mg/2ml 5 amp. glucocorticoid glucocorticoid

about dexamethasone -a potent synthetic glucocorticoid antiasthmatic anti-inflammatory and immunosuppressant. - -mechanism of action of dexamethasone -the drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. this structural change allows it`s migration in to the nucleus and then binding to specific sites on the dna which leads to transcription of specific m-rna and which ultimately regulates protein synthesis. it exerts highly selective glucocorticoid action. it stimulates the enzymes needed to decrease the inflammatory response. - -indications for dexamethasone -1.inflammatory conditions -2.allergic reactions -3.shock -4.anaphylaxis -5.intra-articular and soft tissue inflammation -6.asthma -7.rheumatoid arthritis -8.adrenal insufficiency -9.tuberculous meningitis -10.respiratory diseases -11.malignancies -12.cerebral oedema. -13.acute gout -14.nausea and vomiting