يستعمل دواء ديمرا 20 قرصdimra 20 f.c.tab. cns.analgesic.skeletal muscle relaxant cns.analgesic.skeletal muscle relaxant

about diclofenac potassiumsnsaid anti-inflammatory antipyretic and analgesic.smechanism of action of diclofenac potassiumsdiclofenac possess analgesic anti-inflammatory and antipyretic action. it inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of prostaglandins (((pgs))). it is more potent against cyclo-oxygenase-2 enzyme as compared to other nsaids like indomethacin naproxen etc. it reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake.spharmacokinets of diclofenac potassiumsabsorption: diclofenac potassium is rapidly absorbed after oral administration. it undergoes first pass metabolism. distribution: it is distributed in highly protein bound form. metabolism: diclofenac potassium is metabolised in the liver to mainly 4 hydroxy diclofenac. excretion: drug and metabolites are primarily excreted in urine and some amount in the bile.