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يستعمل دواء دولسيل ام 2/500 مجم 20 قرصdolcyl m 2/500mg 20 f.c. tab anti-diabetic.combined secretagogues+sensitizers anti-diabetic.combined secretagogues+sensitizers
about glimepiride -third-generation sulfonylurea oral antidiabetic agent. -mechanism of action of glimepiride -it is a potent antidiabetic drug which exerts its action by increasing insulin release from the pancreas and by improving glucose tolerance. it acts on the -sulfonylurea receptors- on pancreatic -cell membrane and reduces conductance of atp sensitive k+ channels and thus causes depolarization. this enhances ca2+ influx and degranultion and thus increases insulin secretion rate at any glucose concentration. it primarily increases 2nd phase insulin secretion and has little effect on 1st phase. it also slows hepatic degradation of insulin and minor action of reducing glucagon release and increasing somatostatin release. it also exerts stronger extrapancreatic action; by sensitizing the target tissues such as liver to insulin action. it increases the number of insulin receptors and through a post receptor action improving translation of receptor activation.
تركيبة دواءدولسيل ام 2/500 مجم 20 قرصdolcyl m 2/500mg 20 f.c. tab
يتركب هذا الدواء من :glimepiride+metformin
الشركة المنتجة لدواءدولسيل ام 2/500 مجم 20 قرصdolcyl m 2/500mg 20 f.c. tab
هذا الدواء من انتاج شركة mup
جرعة دواءدولسيل ام 2/500 مجم 20 قرص
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تم استعراض بدائل هذا الدواء 349 مرة