يستعمل دواء جيوكاند بلس 16/1235 مجم 21 قرصgeocand plus 16/12.5mg 21 tab. anti-hypertensive. combined angiotensin blocker with diuretic anti-hypertensive. combined angiotensin blocker with diuretic

about candesartan cilexetil -angiotensin || antagonist antihypertensive agent -mechanism of action of candesartan cilexetil -it is a antagonist of angiotensin 2 at at-1 receptor.it decreases peripheral resistance and lowers bp in hypertensive individuals. it blocks all actions of angiotensin-2 such as 1.vasoconstriction 2. central and peripheral sympathetic stimulus 3. release of aldosterone and adrenaline 4. salt and water reabsorption 5.central actions like thirst vasopressin release and growth promoting actions on heart and blood vessals -indications for candesartan cilexetil -hypertension -interactions for candesartan cilexetil -diuretics and other antihypertensives: increased risk of hypotension -lithium: increased lithium blood level -nsaid: decreased antihypertensive effect -potassium sparing diuretics potassium supplements: increased risk of hyperkalemia