يستعمل دواء لاميزيدين 10 اقراصlamizidine 10 f.c.tab. antiretroviral antiretroviral

about lamivudine -nucleoside reverse transcriptase inhibitor cytidine analogue antiretroviral. -mechanism of action of lamivudine -lamivudine is a deoxy cytidine nucleoside analogue. it undergoes phosphorylation in the presence of kinase enzyme and form lamivudine triphosphate. this lamivudine triphosphate competitively inhibit hiv reverse transcriptase enzyme which is responsible for the conversion of viral rna to pro viral dna and is then added to host cell chromosome. lamivudine triphosphate terminates elongation of pro viral dna and results in inhibition of viral replication. lamivudine triphosphate is also a potent inhibitor of hbv (hepatitis b virus)