يستعمل دواء ماكروفيوران 50مجم 30كبسولmacrofuran 50 mg 30caps. uti infections uti infections

about nitrofurantoin -nitrofuran derivative antibiotic urinary germicide miscellaneous antibiotic. - -mechanism of action of nitrofurantoin -nitrofurantoin is a bacteriostatic drug. it undergoes enzymatic reduction and produces active metabolite which damages the dna of the bacteria. bacteria reduce nitrofurantoin more rapidly than mammalian cells. -indications for nitrofurantoin -1. urinary tract infection -interactions for nitrofurantoin -antichlolinergic drugs: bioavailability of nitrofurantoin increased due to delayed gastric emptying. -probenecid: decreased renal clearance and increased serum levels of nitrofurantoin resulting in toxicity. -magnesium trisilicate: may delay or decrease the absorption of nitrofurantoin. -food: increases bioavailability of nitrofurantoin. -lab tests: serum glucose decreased. elevated serum bilirubin and alkaline phosphates. elevated urinary creatinine levels. false-positive urinary glucose using benedicts reagent.