يستعمل دواء ميتاز 0.1% مرهم 30جمmetaz 0.1% oint. 30 gm anti-inflammatory.glucocorticoid. anti-inflammatory.glucocorticoid.

about mometasone -a glucocorticoid steroid anti psoriatic anti asthma anti inflammatory. -mechanism of action of mometasone -mometasone is a topical medium potency glucocorticoid. the drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. this structural change allows it`s migration in to the nucleus and then binding to specific sites on the dna which leads to transcription of specific m-rna and which ultimately regulates protein synthesis. it exerts highly selective glucocorticoid action. it stimulates the enzymes needed to decrease the inflammatory response. -the drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) induce lipocortins in macrophages endothelium and fibroblasts which inhibits phospholipase a2 and thus decreases the production of prostaglandins leukotrienes (lt) and platelet activating factor